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{"sheet":"Sheet2","index":0,"n_rows":82,"n_cols":12,"rows_kept":82,"cut":false,"hidden":false,"merged":[[2,10,2,11],[2,0,2,2],[2,6,2,9],[2,4,3,4],[2,5,3,5],[2,3,3,3]]}
["Table S2:","Details of PPC dataset"]
[]
["PDB code",null,null,"Complex name","Complex Type","Interface area","Length",null,null,null,"Seqid"]
["Bound","Unbound1","Unbound2",null,null,null,"Bound1","Unbound1","Bound2","Unbound2","Pair 1","Pair 2"]
["1AHW_AB:C ","1FGN_LH ","1TFH_A ","Fab 5g9 <-> Tissue factor ","A ",1899,428,428,200,202,100,98.03]
["1AK4_A:D ","2CPL_ ","1E6J_P ","Cyclophilin <-> HIV capsid ","O ",1029,165,164,145,137,99.39,90.48]
["1AKJ_AB:DE ","2CLR_DE ","1CD8_AB ","MHC class 1 HLA-A2 <-> T-cell CD8 coreceptor ","O ",1995,374,375,228,228,99,100]
["1ATN_A:D ","1IJJ_B ","3DNI_ ","Actin <-> Dnase I ","O ",1774,372,371,258,258,98.66,100]
["1AVX_A:B ","1QQU_A ","1BA7_B ","Porcine trypsin <-> Soybean trypsin inhibitor ","E ",1585,223,223,172,169,99.1,97.11]
["1AY7_A:B ","1RGH_B ","1A19_B ","RNase Sa <-> Barstar ","E ",1237,96,96,89,89,100,98.88]
["1B6C_A:B ","1D6O_A ","1IAS_A ","FKBP binding protein <-> TGFbeta receptor ","O ",1752,107,107,326,330,100,98.79]
["1BGX_HL:T ","1AY1_HL ","1CMW_A ","Fab <-> Taq polymerase ","A ",5814,419,423,828,817,99,97.72]
["1BKD_R:S ","1CTQ_A ","2II0_B ","Ras GTPase <-> Son of sevenless ","O ",3163,166,166,439,463,100,93.97]
["1BUH_A:B ","1HCL_ ","1DKS_A ","CDK2 kinase <-> Ckshs1 ","O ",1324,287,294,70,76,96.6,92.11]
["1BVK_DE:F ","1BVL_BA ","3LZT_ ","Fv Hulys11 <-> HEW lysozyme ","A ",1321,224,224,129,129,100,100]
["1BVN_P:T ","1PIG_ ","1HOE_ ","a-amylase <-> Tendamistat ","E ",2222,496,495,71,74,99.4,95.95]
["1D6R_A:I ","2TGT_ ","1K9B_A ","Bovine trypsin <-> Bowman-Birk inhibitor ","E ",1408,223,223,58,58,100,100]
["1DE4_AB:CF ","1A6Z_AB ","1CX8_AB ","beta2-microglobulin <-> Transferrin receptor ectodom. ","O ",2066,371,371,1270,1278,100,99.06]
["1DFJ_E:I ","9RSA_B ","2BNH_ ","Ribonuclease A <-> Rnase inhibitor ","E ",2582,124,124,456,456,100,100]
["1DQJ_AB:C ","1DQQ_CD ","3LZT_ ","Fab Hyhel63 <-> HEW lysozyme ","A ",1765,424,424,129,129,100,100]
["1E4K_AB:C ","2DTQ_AB ","1FNL_A ","FC fragment of human IgG 1 <-> Human FCGR III ","A ",1634,432,419,172,173,94,98.84]
["1E6E_A:B ","1E1N_A ","1CJE_D ","Adrenoxin reductase <-> Adrenoxin ","E ",2315,457,455,113,107,99.56,94.69]
["1E6J_HL:P ","1E6O_HL ","1A43_ ","Fab <-> HIV-1 capsid protein p24 ","A ",1245,429,429,210,72,100,"33.81 (only one substitution in the aligned region)"]
["1E96_A:B ","1MH1_ ","1HH8_A ","Rac GTPase <-> p67 Phox ","O ",1179,178,183,185,192,96.17,95.83]
["1EAW_A:B ","1EAX_A ","9PTI_ ","Matriptase <-> BPTI ","E ",1866,241,241,56,58,100,96.55]
["1EFN_B:A ","1AVV_A ","1G83_A ","HIV-1-NEF protein <-> SH3 domain ","O ",1254,104,99,57,57,95.19,96.49]
["1EWY_A:C ","1GJR_A ","1CZP_A ","Ferredoxin reductase <-> Ferredoxin ","E ",1502,303,295,98,98,97.03,100]
["1EZU_C:AB","1TRM_A ","1ECZ_AB ","D102N Trypsin <-> Ecotin ","E ",2751,223,223,280,284,99.55,97.18]
["1F34_A:B ","4PEP_ ","1F32_A ","Porcine pepsin <-> Ascaris inhibitor 3 ","E ",3038,325,326,138,127,99.39,92.03]
["1F51_AB:E ","1IXM_AB ","1SRR_C ","Sporulation response factor B <-> Sporulation response factor F ","O ",2407,363,343,119,121,94,98.35]
["1FQ1_A:B ","1B39_A ","1FPZ_F ","CDK inhibitor 3  <->  CDK2 kinase","E ",1832,183,178,295,290,97.27,96.31]
["1FQJ_A:B ","1TND_C ","1FQI_A ","Gt-alpha <-> RGS9 ","O ",1806,317,316,133,133,90.57,92.03]
["1GCQ_B:C ","1GRI_B ","1GCP_B ","GRB2 C-ter SH3 domain <-> Vav N-ter SH3 domain ","O ",1208,57,211,69,67,"27.01 (Identical residues for the aligned segment)",94.29]
["1GHQ_A:B ","1C3D_ ","1LY2_A ","Complement C3 <-> Epstein-Barr virus receptor CR2 ","O ",800,307,294,129,130,95.77,97.69]
["1GPW_A:B ","1THF_D ","1K9V_F ","HISF protein <-> Amidotransferase HISH ","O ",2097,253,253,200,200,99.21,100]
["1GRN_A:B","1A4R_A ","1RGP_ ","CDC42 GTPase <-> CDC42 GAP ","O ",2332,191,190,197,189,98.95,92.04]
["1HE1_C:A ","1MH1_ ","1HE9_A ","Rac GTPase <-> Pseudomonas toxin GAP dom. ","O ",2113,176,183,135,131,95.63,"86.52 (1 substitution in the aligned region)"]
["1HE8_B:A ","821P_ ","1E8Z_A ","Ras GTPase <-> PIP3 kinase ","O ",1305,749,839,166,166,99.4,"84.28 (2 substitutions in the aligned segment)"]
["1HIA_AB:I ","2PKA_XY ","1BX8_ ","Kallikrein <-> Hirustatin ","E ",1737,230,232,48,49,99,97.96]
["1I2M_A:B ","1QG4_A ","1A12_A ","Ran GTPase <-> RCC1 ","O ",2779,165,202,388,401,"81.19 (1 substitution in the aligned region)",96.76]
["1I4D_D:AB ","1MH1_ ","1I49_AB ","Rac GTPase <-> Arfaptin ","O ",1657,177,183,373,402,96.17,92]
["1J2J_A:B ","1O3Y_A ","1OXZ_A ","Arf1 GTPase <-> GAT domain of GGA1 ","O ",1209,165,166,41,39,99.4,90.48]
["1JPS_HL:T ","1JPT_HL ","1TFH_B ","Fab D3H44 <-> Tissue factor ","A ",1852,426,425,200,182,99.75,91]
["1KKL_ABC:H ","1JB1_ABC ","2HPR_ ","HPr kinase C-ter domain <-> HPr ","E ",1641,501,471,86,87,92.8,95.4]
["1KTZ_A:B ","1TGK_ ","1M9Z_A ","TGF-beta <-> TGF-beta receptor ","O ",989,82,112,106,105,"73.21 (Identical residues in the aligned segment)",97.17]
["1KXP_A:D ","1IJJ_B ","1KW2_B ","Actin <-> Vitamin D binding protein ","O ",3341,349,371,438,453,94.07,94.54]
["1M10_A:B ","1AUQ_ ","1M0Z_B ","Von willebrand factor dom. A1 <-> Glycoprotein IB-a ","E ",2097,199,208,267,266,95.19,99.25]
["1ML0_AB:D ","1MKF_AB ","1DOL_ ","Viral chemokine binding p. M3 <-> Chemokine Mcp1 ","O ",2069,742,742,64,71,100,"84.72 (2 substitutions in the aligned segment)"]
["1MLC_AB:E ","1MLB_AB ","3LZT_ ","Fab44.1 <-> HEW lysozyme ","A ",1392,432,432,129,129,100,100]
["1N2C_ABCD:EF ","3MIN_ABCD ","2NIP_AB ","Nitrogenase Mo-Fe protein <-> Nitrogenase Fe protein ","O ",3635,2000,1979,548,575,99,95.5]
["1OPH_A:B ","1QLP_A ","1UTQ_A ","a-1-antitrypsin <-> Trypsinogen ","E ",1360,375,372,223,223,96.8,99.55]
["1PXV_A:C ","1X9Y_A ","1NYC_A ","Cystein protease <-> Cystein protease inhibitor ","E ",2336,183,175,111,111,90.91,100]
["1QA9_A:B ","1HNF_ ","1CCZ_A ","CD2 <-> CD58 ","O ",1353,102,179,95,171,"55.31 (3 substitutions in the aligned segment)","51.46 (6 substitutions in the aligned segment)"]
["1R8S_A:E ","1HUR_A ","1R8M_E ","Arf1 GTPase <-> Sec 7 domain ","O ",2986,160,180,187,195,"88.89 (Identical residues in the aligned region)",91.92]
["1SBB_A:B ","1BEC_ ","1SE4_ ","T-cell receptor beta <-> Staphylococcus enterotoxin B ","O ",1064,238,238,239,239,100,100]
["1T6B_X:Y ","1ACC_A ","1SHU_X ","Anthrax protective antigen <-> Anthrax toxin receptor ","O ",1948,676,665,170,181,96.92,93.92]
["1TMQ_A:B ","1JAE_ ","1B1U_A ","alpha-amylase <-> RAGI inhibitor ","E ",2401,470,470,117,117,100,95.8]
["1UDI_E:I ","1UDH_ ","2UGI_B ","Uracyl-DNA glycosylase <-> Glycosylase inhibitor ","E ",2022,227,228,83,83,99.56,100]
["1VFB_AB:C ","1VFA_AB ","8LYZ_ ","Fv D1.3 <-> HEW lysozyme ","A ",1383,223,224,129,129,99.5,100]
["1WEJ_HL:F ","1QBL_HL ","1HRC_ ","Fab E8 <-> Cytochrome C ","A ",1177,437,433,104,104,99,100]
["1WQ1_R:G","6Q21_D ","1WER_ ","Ras GTPase <-> Ras GAP ","O ",2913,166,171,320,324,97.08,98.77]
["1XD3_A:B ","1UCH ","1YJ1_A ","UCH-L3 <-> Ubiquitin ","O ",2281,229,206,75,70,"89.96 (Identical residues in the aligned region)",92]
["1XQS_A:C ","1XQR_A ","1S3X_A ","HspBP1 <-> Hsp70 ATPase domain ","O ",2350,264,259,165,193,94.76,"85.49 (Identical residues in the aligned region)"]
["1Y64_A:B ","2FXU_A ","1UX5_A ","Actin <-> BNI1 protein ","O ",2745,356,360,411,411,98.34,100]
["1YVB_A:I ","2GHU_A ","1CEW_I ","Falcipain 2 <-> Cystatin ","E ",1743,241,241,111,108,100,97.3]
["1Z0K_A:B ","2BME_A ","1YZM_A ","Rab4A GTPase <-> RAB4 binding domain of Rabenosyn ","O ",1787,169,176,61,46,94.89,"72.13 (2 substitutions in the aligned region)"]
["1Z5Y_D:E ","1L6P ","2B1K_A ","N-term of DsbD <-> E.coli CCMG protein ","O ",1346,118,121,136,149,91.79,"86.72 (1 substitution in the aligned region)"]
["2B42_B:A ","2DCY_A ","1T6E_X ","Xylanase <-> Xylanase inhibitor ","E ",2520,184,185,364,362,98.92,94.35]
["2BTF_A:P ","1IJJ_B ","1PNE_ ","Actin <-> Profilin ","O ",2063,374,371,139,139,93.05,100]
["2H7V_A:C ","1MH1_ ","2H7O_A ","Rac GTPase <-> YpkA ","O ",1574,182,183,269,270,96.76,94.58]
["2HQS_A:H ","1CRZ_A ","1OAP_A ","TolB <-> Pal ","O ",2333,412,397,108,108,95.63,98.17]
["2I25_N:L ","2I24_N ","3LZT ","Shark single domain antigen receptor <-> Lysozyme ","A ",1425,114,113,129,129,99.12,100]
["2NZ8_A:B ","1MH1_ ","1NTY_A ","Rac GTPase <-> DH/PH domain of TRIO ","O ",2599,177,183,279,305,95.63,91.48]
["2O8V_A:B ","1SUR_A ","2TRX_A ","PAPS reductase <-> Thioredoxin ","E ",1619,229,215,108,108,93.89,99.07]
["2OOB_A:B ","2OOA_A ","1YJ1_A ","Ubiquitin ligase <-> Ubiquitin ","O ",808,72,70,44,41,95.83,"88.89 (1 substitution in the aligned region)"]
["2OT3_B:A ","1YZU_A ","1TXU_A ","Rab21 GTPase <-> Rabex-5 VPS9 domain ","O ",2306,253,245,157,165,91.47,93.37]
["2PCC_A:B ","1CCP_ ","1YCC_ ","Cyt C peroxidase <-> Cytochrome C ","E ",1141,294,293,108,108,99.66,100]
["2SIC_E:I ","1SUP_ ","3SSI_ ","Subtilisin <-> Streptomyces subtilisin inhibitor ","E ",1617,275,275,107,108,100,99.07]
["2SNI_E:I ","1UBN_A ","2CI2_I ","Subtilisin <-> Chymotrypsin inhibitor 2 ","E ",1628,275,274,64,65,99.27,98.46]
["2UUY_A:B ","1HJ9_A ","2UUX_A ","Trypsin <-> Tryptase inhibitor from tick ","E ",1280,223,223,52,55,100,92.73]
[]
["E - enzyme-inhibitor complex, A - antigen-antibody complex, O - other complex"]

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