<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of inserm-00663723</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-01T22:30:56+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Influence of hydrological conditions on the Escherichia coli population structure in the water of a creek on a rural watershed.</title>
            <author role="crp">
              <persName>
                <forename type="first">M.</forename>
                <surname>Ratajczak</surname>
              </persName>
              <email type="md5">7b25071080140460e73f033ee1ffa193</email>
              <email type="domain">etu.univ-rouen.fr</email>
              <idno type="idhal" notation="numeric">965205</idno>
              <idno type="halauthorid" notation="string">93468-965205</idno>
              <affiliation ref="#struct-186205"/>
              <affiliation ref="#struct-847"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">E.</forename>
                <surname>Laroche</surname>
              </persName>
              <email type="md5">4f7f576e70c3eefbeb26811336c1b3ce</email>
              <email type="domain">etu.univ-rouen.fr</email>
              <idno type="idhal" notation="numeric">965206</idno>
              <idno type="halauthorid" notation="string">856195-965206</idno>
              <affiliation ref="#struct-186205"/>
              <affiliation ref="#struct-847"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Thierry</forename>
                <surname>Berthe</surname>
              </persName>
              <email type="md5">5b08b5ada56246fca3ee1edf7f4ebb29</email>
              <email type="domain">univ-rouen.fr</email>
              <idno type="idhal" notation="string">thierry-berthe</idno>
              <idno type="idhal" notation="numeric">19116</idno>
              <idno type="halauthorid" notation="string">8132-19116</idno>
              <idno type="IDREF">https://www.idref.fr/182201104</idno>
              <affiliation ref="#struct-186205"/>
              <affiliation ref="#struct-847"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">O.</forename>
                <surname>Clermont</surname>
              </persName>
              <email type="md5">f54ae37b68f8646dabeef072db1bf910</email>
              <email type="domain">iserm.fr</email>
              <idno type="idhal" notation="numeric">965207</idno>
              <idno type="halauthorid" notation="string">901697-965207</idno>
              <affiliation ref="#struct-3080"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">B.</forename>
                <surname>Pawlak</surname>
              </persName>
              <email type="md5">cabf4627fcd77f5a4cc999fb07646c06</email>
              <email type="domain">univ-rouen.fr</email>
              <idno type="idhal" notation="string">barbara-pawlak</idno>
              <idno type="idhal" notation="numeric">181841</idno>
              <idno type="halauthorid" notation="string">201412-181841</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5569-9790</idno>
              <idno type="IDREF">https://www.idref.fr/178840920</idno>
              <affiliation ref="#struct-186205"/>
              <affiliation ref="#struct-847"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">E.</forename>
                <surname>Denamur</surname>
              </persName>
              <email type="md5">33e13a7f013f48c94ea2db9b477e71f2</email>
              <email type="domain">iserm.fr</email>
              <idno type="idhal" notation="numeric">965208</idno>
              <idno type="halauthorid" notation="string">901698-965208</idno>
              <affiliation ref="#struct-3080"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">F.</forename>
                <surname>Petit</surname>
              </persName>
              <email type="md5">25d30b1d792ced4a34ba00357290f3e6</email>
              <email type="domain">univ-rouen.fr</email>
              <idno type="idhal" notation="string">fabienne-petit</idno>
              <idno type="idhal" notation="numeric">181334</idno>
              <idno type="halauthorid" notation="string">107988-181334</idno>
              <idno type="IDREF">https://www.idref.fr/07732790X</idno>
              <affiliation ref="#struct-186205"/>
              <affiliation ref="#struct-847"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Ed.</forename>
                <surname>BMC</surname>
              </persName>
              <email type="md5">7bc004cf734e1645c1468c005ceafbd9</email>
              <email type="domain">biomedcentral.com.invalid</email>
            </editor>
            <funder>MR held a research grant from the "Conseil Régional de Haute Normandie" (France). ED was partially supported by the "Fondation pour la Recherche Médicale".</funder>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2012-01-27 14:16:43</date>
              <date type="whenModified">2024-12-02 14:48:10</date>
              <date type="whenReleased">2012-03-05 09:44:47</date>
              <date type="whenProduced">2010</date>
              <date type="whenEndEmbargoed">2012-01-27</date>
              <ref type="file" target="https://inserm.hal.science/inserm-00663723v1/document">
                <date notBefore="2012-01-27"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://inserm.hal.science/inserm-00663723v1/file/1471-2180-10-222.pdf" id="file-663723-598701">
                <date notBefore="2012-01-27"/>
              </ref>
              <ref type="annex" subtype="other" n="0" target="https://inserm.hal.science/inserm-00663723v1/file/1471-2180-10-222-S1.DOC" id="file-663723-598696">
                <date notBefore="2012-01-27"/>
              </ref>
              <ref type="annex" subtype="other" n="0" target="https://inserm.hal.science/inserm-00663723v1/file/1471-2180-10-222.xml" id="file-663723-598693">
                <date notBefore="2012-01-27"/>
              </ref>
              <ref type="externalLink" target="https://bmcmicrobiol.biomedcentral.com/track/pdf/10.1186/1471-2180-10-222"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="151596">
                <persName>
                  <forename>Ed.</forename>
                  <surname>BMC</surname>
                </persName>
                <email type="md5">7bc004cf734e1645c1468c005ceafbd9</email>
                <email type="domain">biomedcentral.com.invalid</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">inserm-00663723</idno>
            <idno type="halUri">https://inserm.hal.science/inserm-00663723</idno>
            <idno type="halBibtex">ratajczak:inserm-00663723</idno>
            <idno type="halRefHtml">&lt;i&gt;BMC Microbiology&lt;/i&gt;, 2010, 10 (1), pp.222. &lt;a target="_blank" href="https://dx.doi.org/10.1186/1471-2180-10-222"&gt;&amp;#x27E8;10.1186/1471-2180-10-222&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">BMC Microbiology, 2010, 10 (1), pp.222. &amp;#x27E8;10.1186/1471-2180-10-222&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://about.hal.science/hal-authorisation-v1/">HAL Authorization<ref corresp="#file-663723-598701"/><ref corresp="#file-663723-598696"/><ref corresp="#file-663723-598693"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="INSU">INSU - Institut National des Sciences de l'Univers</idno>
            <idno type="stamp" n="UNIV-PARIS7" corresp="UNIV-PARIS">Université Denis Diderot - Paris VII</idno>
            <idno type="stamp" n="UNIV-PARIS13">Université Paris-Nord - Paris XIII </idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="COMUE-NORMANDIE">Normandie Université</idno>
            <idno type="stamp" n="M2C">Production scientifique de l'UMR 6143 - M2C</idno>
            <idno type="stamp" n="UNIROUEN">Université de Rouen Normandie</idno>
            <idno type="stamp" n="UNILEHAVRE">Université Le Havre Normandie</idno>
            <idno type="stamp" n="UNICAEN">Université de Caen Normandie</idno>
            <idno type="stamp" n="SORBONNE-PARIS-NORD">Université Sorbonne Paris Nord</idno>
            <idno type="stamp" n="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="ACT-R" corresp="UNIV-PARIS13">Act'R </idno>
            <idno type="stamp" n="FRM">Fondation pour la Recherche Médicale</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Influence of hydrological conditions on the Escherichia coli population structure in the water of a creek on a rural watershed.</title>
                <author role="crp">
                  <persName>
                    <forename type="first">M.</forename>
                    <surname>Ratajczak</surname>
                  </persName>
                  <email type="md5">7b25071080140460e73f033ee1ffa193</email>
                  <email type="domain">etu.univ-rouen.fr</email>
                  <idno type="idhal" notation="numeric">965205</idno>
                  <idno type="halauthorid" notation="string">93468-965205</idno>
                  <affiliation ref="#struct-186205"/>
                  <affiliation ref="#struct-847"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">E.</forename>
                    <surname>Laroche</surname>
                  </persName>
                  <email type="md5">4f7f576e70c3eefbeb26811336c1b3ce</email>
                  <email type="domain">etu.univ-rouen.fr</email>
                  <idno type="idhal" notation="numeric">965206</idno>
                  <idno type="halauthorid" notation="string">856195-965206</idno>
                  <affiliation ref="#struct-186205"/>
                  <affiliation ref="#struct-847"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Thierry</forename>
                    <surname>Berthe</surname>
                  </persName>
                  <email type="md5">5b08b5ada56246fca3ee1edf7f4ebb29</email>
                  <email type="domain">univ-rouen.fr</email>
                  <idno type="idhal" notation="string">thierry-berthe</idno>
                  <idno type="idhal" notation="numeric">19116</idno>
                  <idno type="halauthorid" notation="string">8132-19116</idno>
                  <idno type="IDREF">https://www.idref.fr/182201104</idno>
                  <affiliation ref="#struct-186205"/>
                  <affiliation ref="#struct-847"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">O.</forename>
                    <surname>Clermont</surname>
                  </persName>
                  <email type="md5">f54ae37b68f8646dabeef072db1bf910</email>
                  <email type="domain">iserm.fr</email>
                  <idno type="idhal" notation="numeric">965207</idno>
                  <idno type="halauthorid" notation="string">901697-965207</idno>
                  <affiliation ref="#struct-3080"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">B.</forename>
                    <surname>Pawlak</surname>
                  </persName>
                  <email type="md5">cabf4627fcd77f5a4cc999fb07646c06</email>
                  <email type="domain">univ-rouen.fr</email>
                  <idno type="idhal" notation="string">barbara-pawlak</idno>
                  <idno type="idhal" notation="numeric">181841</idno>
                  <idno type="halauthorid" notation="string">201412-181841</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5569-9790</idno>
                  <idno type="IDREF">https://www.idref.fr/178840920</idno>
                  <affiliation ref="#struct-186205"/>
                  <affiliation ref="#struct-847"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">E.</forename>
                    <surname>Denamur</surname>
                  </persName>
                  <email type="md5">33e13a7f013f48c94ea2db9b477e71f2</email>
                  <email type="domain">iserm.fr</email>
                  <idno type="idhal" notation="numeric">965208</idno>
                  <idno type="halauthorid" notation="string">901698-965208</idno>
                  <affiliation ref="#struct-3080"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">F.</forename>
                    <surname>Petit</surname>
                  </persName>
                  <email type="md5">25d30b1d792ced4a34ba00357290f3e6</email>
                  <email type="domain">univ-rouen.fr</email>
                  <idno type="idhal" notation="string">fabienne-petit</idno>
                  <idno type="idhal" notation="numeric">181334</idno>
                  <idno type="halauthorid" notation="string">107988-181334</idno>
                  <idno type="IDREF">https://www.idref.fr/07732790X</idno>
                  <affiliation ref="#struct-186205"/>
                  <affiliation ref="#struct-847"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">346</idno>
                <idno type="issn">1471-2180</idno>
                <title level="j">BMC Microbiology</title>
                <imprint>
                  <publisher>BioMed Central</publisher>
                  <biblScope unit="volume">10</biblScope>
                  <biblScope unit="issue">1</biblScope>
                  <biblScope unit="pp">222</biblScope>
                  <date type="datePub">2010</date>
                  <date type="dateEpub">2010-08-19</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1186/1471-2180-10-222</idno>
              <idno type="pubmed">20723241</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="mesh">Anti-Bacterial Agents</classCode>
              <classCode scheme="mesh">Climate Change</classCode>
              <classCode scheme="mesh">Seasons</classCode>
              <classCode scheme="mesh">Water Microbiology</classCode>
              <classCode scheme="mesh">Drug Resistance, Bacterial</classCode>
              <classCode scheme="mesh">Ecosystem</classCode>
              <classCode scheme="mesh">Escherichia coli</classCode>
              <classCode scheme="mesh">Escherichia coli Proteins</classCode>
              <classCode scheme="mesh">France</classCode>
              <classCode scheme="mesh">Hemolysin Proteins</classCode>
              <classCode scheme="mesh">Phylogeny</classCode>
              <classCode scheme="halDomain" n="sdv.mp">Life Sciences [q-bio]/Microbiology and Parasitology</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>BACKGROUND: Escherichia coli is a commensal bacterium of the gastro-intestinal tract of human and vertebrate animals, although the aquatic environment could be a secondary habitat. The aim of this study was to investigate the effect of hydrological conditions on the structure of the E. coli population in the water of a creek on a small rural watershed in France composed of pasture and with human occupation. RESULTS: It became apparent, after studying the distribution in the four main E. coli phylo-groups (A, B1, B2, D), the presence of the hly (hemolysin) gene and the antibiotic resistance pattern, that the E. coli population structure was modified not only by the hydrological conditions (dry versus wet periods, rainfall events), but also by how the watershed was used (presence or absence of cattle). Isolates of the B1 phylo-group devoid of hly and sensitive to antibiotics were particularly abundant during the dry period. During the wet period and the rainfall events, contamination from human sources was predominantly characterized by strains of the A phylo-group, whereas contamination by cattle mainly involved B1 phylo-group strains resistant to antibiotics and exhibiting hly. As E. coli B1 was the main phylo-group isolated in water, the diversity of 112 E. coli B1 isolates was further investigated by studying uidA alleles (beta-D-glucuronidase), the presence of hly, the O-type, and antibiotic resistance. Among the forty epidemiolgical types (ETs) identified, five E. coli B1 ETs were more abundant in slightly contaminated water. CONCLUSIONS: The structure of an E. coli population in water is not stable, but depends on the hydrological conditions and on current use of the land on the watershed. In our study it was the ratio of A to B1 phylo-groups that changed. However, a set of B1 phylo-group isolates seems to be persistent in water, strengthening the hypothesis that they may correspond to specifically adapted strains.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="regrouplaboratory" xml:id="struct-186205" status="VALID">
          <idno type="RNSR">200810763U</idno>
          <orgName>Sciences Appliquées à L'Environnement</orgName>
          <orgName type="acronym">SCALE</orgName>
          <date type="start">2008-01-01</date>
          <desc>
            <address>
              <addrLine>Place Émile Blondel 76821 Mont-Saint-Aignan Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://scale.crihan.fr/</ref>
          </desc>
          <listRelation>
            <relation name="FED 4116" active="#struct-300317" type="direct"/>
            <relation active="#struct-455934" type="indirect"/>
            <relation name="FED 4116" active="#struct-300318" type="direct"/>
            <relation name="FR3730" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-847" status="VALID">
          <idno type="IdRef">184390478</idno>
          <idno type="RNSR">200012210B</idno>
          <idno type="ROR">https://ror.org/05k1a6w82</idno>
          <idno type="Wikidata">Q51783493</idno>
          <orgName>Morphodynamique Continentale et Côtière</orgName>
          <orgName type="acronym">M2C</orgName>
          <date type="start">1996-01-01</date>
          <desc>
            <address>
              <addrLine>24 rue des Tilleuls 14000 Caen</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.unicaen.fr/m2c</ref>
          </desc>
          <listRelation>
            <relation active="#struct-7127" type="direct"/>
            <relation active="#struct-455934" type="indirect"/>
            <relation active="#struct-300045" type="direct"/>
            <relation active="#struct-300318" type="direct"/>
            <relation name="UMR6143" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-3080" status="OLD">
          <orgName>Ecologie et Evolution des Microorganismes</orgName>
          <orgName type="acronym">EEM</orgName>
          <desc>
            <address>
              <addrLine>UFR de Médecine, Université Paris 7 Denis Diderot 16, rue Henri Huchard, B.P. 416, 75870 Paris cedex 18.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.bichat.inserm.fr/equipes/emi0339/u722.html</ref>
          </desc>
          <listRelation>
            <relation active="#struct-15786" type="direct"/>
            <relation active="#struct-300301" type="direct"/>
            <relation active="#struct-303171" type="direct"/>
            <relation name="U722" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300317" status="VALID">
          <idno type="IdRef">031308570</idno>
          <idno type="ISNI">0000000121731046</idno>
          <idno type="ROR">https://ror.org/05v509s40</idno>
          <orgName>Université Le Havre Normandie</orgName>
          <orgName type="acronym">ULH</orgName>
          <date type="start">1984-08-27</date>
          <desc>
            <address>
              <addrLine>25 rue Philippe Lebon - BP 1123 - 76063 Le Havre Cedex France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-lehavre.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-455934" status="VALID">
          <idno type="IdRef">190906332</idno>
          <idno type="ISNI">0000000417859671 </idno>
          <idno type="ROR">https://ror.org/01k40cz91</idno>
          <orgName>Normandie Université</orgName>
          <orgName type="acronym">NU</orgName>
          <date type="start">2015-01-01</date>
          <desc>
            <address>
              <addrLine>Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.normandie-univ.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300318" status="VALID">
          <idno type="IdRef">026403919</idno>
          <idno type="ISNI">0000000121083034</idno>
          <idno type="ROR">https://ror.org/03nhjew95</idno>
          <orgName>Université de Rouen Normandie</orgName>
          <orgName type="acronym">UNIROUEN</orgName>
          <date type="start">1966-01-01</date>
          <desc>
            <address>
              <addrLine>1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-rouen.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-7127" status="VALID">
          <idno type="IdRef">026403064</idno>
          <idno type="ISNI">0000000121864076</idno>
          <idno type="ROR">https://ror.org/051kpcy16</idno>
          <orgName>Université de Caen Normandie</orgName>
          <orgName type="acronym">UNICAEN</orgName>
          <date type="start">1432-01-01</date>
          <desc>
            <address>
              <addrLine>Esplanade de la Paix - CS 14032 - 14032 CAEN Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.unicaen.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300045" status="VALID">
          <idno type="IdRef">029349265</idno>
          <idno type="ISNI">0000 0001 2154 1736</idno>
          <idno type="ROR">https://ror.org/04kdfz702</idno>
          <idno type="Wikidata">Q3152437</idno>
          <orgName>Institut national des sciences de l'Univers</orgName>
          <orgName type="acronym">INSU - CNRS</orgName>
          <date type="start">2007-04-19</date>
          <desc>
            <address>
              <addrLine>INSU-CNRS3 rue Michel-Ange, 75794 Paris Cedex 16</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.insu.cnrs.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-15786" status="VALID">
          <idno type="ROR">https://ror.org/05f82e368</idno>
          <orgName>Université Paris 13</orgName>
          <orgName type="acronym">UP13</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-paris13.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300301" status="OLD">
          <idno type="IdRef">027542084</idno>
          <idno type="ISNI">0000000121514068</idno>
          <idno type="ROR">https://ror.org/02n7qrg46</idno>
          <orgName>Université Paris Diderot - Paris 7</orgName>
          <orgName type="acronym">UPD7</orgName>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>5 rue Thomas-Mann - 75205 Paris cedex 13</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-paris-diderot.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-303171" status="VALID">
          <idno type="IdRef">19077990X</idno>
          <idno type="ROR">https://ror.org/001z21q04</idno>
          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>