Influence of oxygen tension on CD133 phenotype in human glioma cell cultures. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Cancer Letters Year : 2007

Influence of oxygen tension on CD133 phenotype in human glioma cell cultures.

Abstract

Under standard culture conditions, tumor cells are exposed to 20% O(2), whereas the mean tumor oxygen levels within the tumor are much lower. We demonstrate, using low-passaged human tumor cell cultures established from glioma, that a reduction in the oxygen level in these cell cultures dramatically increases the percentage of CD133 expressing cells.
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Dates and versions

inserm-00382779 , version 1 (31-07-2009)

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Nadine Platet, Shi Yong Liu, Michèle El Atifi, Lisa Oliver, François M. Vallette, et al.. Influence of oxygen tension on CD133 phenotype in human glioma cell cultures.. Cancer Letters, 2007, 258 (2), pp.286-90. ⟨10.1016/j.canlet.2007.09.012⟩. ⟨inserm-00382779⟩
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