%0 Journal Article %T Results of transurethral injection of silicone micro-implants for females with intrinsic sphincter deficiency. %T Transurethral injection of silicone microimplants %+ CHU Rothschild [AP-HP] %A Barranger, Emmanuel %A Fritel, Xavier, * %A Kadoch, Olivier %A Liou, Yveline %A Pigné, Alain %< avec comité de lecture %@ 0022-5347 %J Journal of Urology %I Elsevier %V 164 %N 5 %P 1619-22 %8 2000-11 %D 2000 %M 11025718 %K urodynamics/ urinary incontinence/ stress/ silicone injections/ treatment outcome. %K urodynamics/ urinary incontinence/ stress/ silicone injections/ treatment outcome %Z Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetricsJournal articles %X PURPOSE: We evaluated the medium term efficiency of silicone micro-implants injected in women with intrinsic sphincter deficiency. MATERIALS AND METHODS: A total of 21 women with intrinsic sphincter deficiency underwent transurethral injection of silicone micro-implants between August 1996 and February 1997. Each patient was assessed preoperatively by questionnaire, physical examination and urodynamic study. The results were evaluated by questionnaire at 1 month, and 1 and 2 years after silicone injection. The outcome was classified as dry in all circumstances, improved or failure. RESULTS: All patients (median age 68 years, range 46 to 83) had undergone previous anti-incontinence or prolapse surgeries. At 1 month 2 patients (10%) were dry and 9 (42%) were improved, and treatment failed in 10 (48%). At 1 year (median 16 months, range 14 to 22) 2 cases (10%) were classified as dry, 8 (38%) improved and 11 (52%) failures. At last followup (median 31 months, range 24 to 34) 4 cases (19%) were classified as dry, 6 (29%) improved and 11 (52%) failures. None of the 6 patients with bladder neck hypermobility was dry. CONCLUSIONS: Our results of silicone transurethral injection are disappointing but comparable to other bulking agents without a time dependent decrease in efficiency. The use of silicone micro-implants is an alternative for the treatment of intrinsic sphincter deficiency in patients without bladder neck hypermobility and in whom the sling procedure has failed. %G English %2 https://inserm.hal.science/inserm-00370129/document %2 https://inserm.hal.science/inserm-00370129/file/92-12-142.pdf %L inserm-00370129 %U https://inserm.hal.science/inserm-00370129 %~ INSERM %~ APHP %~ SORBONNE-UNIVERSITE %~ SU-INF-2018 %~ SU-MEDECINE %~ SU-MED %~ SU-TI %~ ALLIANCE-SU