%0 Journal Article %T [Survivin, the starlet of the passenger protein complex. Check-up for its tenth anniversary.] %+ Institut d'oncologie/développement Albert Bonniot de Grenoble (INSERM U823) %A Delacour-Larose, Marlène %A Nhung Hoang, Thi My %A Molla, Annie %< avec comité de lecture %@ 0767-0974 %J Médecine/Sciences %I EDP Sciences %V 24 %N 10 %P 828-32 %8 2008-10 %D 2008 %M 18950578 %Z Life Sciences [q-bio]/GeneticsJournal articles %X Ten year after its discovery Survivin has gained a strategic place within the chromosomal passenger complex. Whereas INCENP, Borealin and Aurora B are fully immobile in the complex, Survivin is mobile on centromere. Its mobility is regulated both by phosphorylation and ubiquitination. Survivin is a dynamic messenger that senses the central spindle tension and participates to the control of the mitotic chekpoint. In this review, we have detailed the multiple mitotic activities of Survivin and discussed them in light of the recent reported cristallographic data. %G French %2 https://inserm.hal.science/inserm-00336277/document %2 https://inserm.hal.science/inserm-00336277/file/DelacourMSR1.pdf %2 https://inserm.hal.science/inserm-00336277/file/Survivine-delacour.pdf %L inserm-00336277 %U https://inserm.hal.science/inserm-00336277 %~ INSERM %~ UGA %~ UNIV-GRENOBLE1 %~ M-S %~ U823